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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
16.97
Human Site:
S557
Identified Species:
23.33
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S557
P
S
V
L
T
T
P
S
K
I
E
P
M
K
A
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S557
P
S
V
L
T
T
P
S
K
I
E
P
M
K
A
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S678
P
S
V
L
T
T
P
S
K
I
E
P
M
K
A
Dog
Lupus familis
XP_543550
1017
111618
S557
P
S
V
L
T
T
P
S
K
I
E
P
M
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
K557
S
V
L
T
T
P
S
K
I
E
P
M
K
A
F
Rat
Rattus norvegicus
NP_001129232
1015
111665
K557
S
V
L
T
T
P
S
K
I
E
P
M
K
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S557
A
P
P
A
S
S
S
S
V
L
T
T
P
S
K
Frog
Xenopus laevis
Q8QFR2
1013
112021
I557
S
I
T
A
Q
P
K
I
E
P
M
K
A
L
D
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
K557
A
S
K
I
E
P
M
K
A
L
D
S
R
F
T
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
M557
S
A
S
K
I
E
P
M
K
A
L
D
S
R
F
Fruit Fly
Dros. melanogaster
O17468
1047
113397
T554
S
N
L
N
V
T
A
T
G
K
S
E
F
V
K
Honey Bee
Apis mellifera
XP_001122939
838
91355
T403
V
P
S
T
Q
T
T
T
L
L
N
T
N
L
H
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
P500
E
G
K
K
T
V
A
P
P
P
A
K
R
K
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
P529
Q
R
M
N
G
T
K
P
S
Y
G
S
N
S
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
V557
A
T
I
T
E
S
L
V
I
E
K
V
P
G
T
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
R405
K
N
M
E
Q
L
Y
R
Y
G
V
D
K
D
S
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
L555
R
G
G
I
A
A
M
L
L
G
N
K
R
K
A
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
N.A.
6.6
0
6.6
13.3
6.6
6.6
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
13.3
N.A.
N.A.
26.6
6.6
26.6
26.6
26.6
20
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
0
0
13.3
P-Site Similarity:
N.A.
13.3
N.A.
26.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
6
0
12
6
6
12
0
6
6
6
0
6
12
36
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
6
12
0
6
6
% D
% Glu:
6
0
0
6
12
6
0
0
6
18
24
6
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
6
6
18
% F
% Gly:
0
12
6
0
6
0
0
0
6
12
6
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% H
% Ile:
0
6
6
12
6
0
0
6
18
24
0
0
0
0
0
% I
% Lys:
6
0
12
12
0
0
12
18
30
6
6
18
18
36
12
% K
% Leu:
0
0
18
24
0
6
6
6
12
18
6
0
0
12
0
% L
% Met:
0
0
12
0
0
0
12
6
0
0
6
12
24
0
0
% M
% Asn:
0
12
0
12
0
0
0
0
0
0
12
0
12
0
6
% N
% Pro:
24
12
6
0
0
24
30
12
6
12
12
24
12
0
0
% P
% Gln:
6
0
0
0
18
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
6
6
0
0
0
0
0
6
0
0
0
0
18
6
0
% R
% Ser:
30
30
12
0
6
12
18
30
6
0
6
12
6
12
6
% S
% Thr:
0
6
6
24
42
42
6
12
0
0
6
12
0
0
12
% T
% Val:
6
12
24
0
6
6
0
6
6
0
6
6
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
0
6
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _